ess3.jpgAdvisor Spotlight: Caldwell B. Esselstyn, Jr., MD

Making Yourself
Heart Attack Proof


I caught up with Dr. Esselstyn while he was in Missoula, Montana to give a talk to oral surgeons, dentists and their families about "making yourself heart attack proof," which has been his passion and expertise for more than twenty years.

Caldwell B. Esselstyn, Jr., received his B.A. from Yale University and his M.D. from Western Reserve University. In 1956, pulling the No. 6 oar as a member of the victorious United States rowing team, he was awarded a gold medal at the Olympic Games. He was later trained as a surgeon at the Cleveland Clinic and at St. George's Hospital in London. Dr. Esselstyn has been associated with the Cleveland Clinic since 1968. During that time, he has served as President of the Staff and as a member of the Board of Governors. He chaired the Clinic's Breast Cancer Task Force and headed its Section of Thyroid and Parathyroid Surgery.
 
It was during his years on the breast cancer task force that he became increasing disenchanted with the fact that no matter how many breast operations he was doing, he was not doing anything to protect the next unsuspecting victim. This was particularly frustrating given that research studies had already suggested an obvious culprit. The fatty American diet was, in all likelihood, responsible for heart disease as well as many Western cancers-- illnesses which are infrequently seen in parts of the world where much less fat is consumed. This quandry compelled him into a global research project and his ground-breaking work addressing the leading cause of death in the United States for men and women: heart disease.

Dr. Esselstyn notes: "The world's advanced countries have easy access to plentiful high fat food; ironically, it is this rich diet that produces atherosclerosis. In the world's poorer nations, many people subsist on a primarily plant-based diet, which is far healthier, especially in terms of heart disease. To treat coronary heart disease, a century of scientific investigation has produced a device-driven, risk factor-oriented strategy. Nevertheless, many patients treated with this approach experience progressive disability and death. This strategy is a rear-guard defensive approach.
 
In contrast, compelling data from nutritional studies, population surveys, and interventional studies supports the effectiveness of a plant-based diet and aggressive lipid-lowering to arrest, prevent, and selectively reverse heart disease. In essence, this is an offensive strategy. The single biggest step toward adopting this strategy would be to have United States dietary guidelines support a plant-based diet. An expert committee purged of industrial and political influence is required to assure that science is the basis for dietary recommendations." (Preventive Cardiology, 2001)
 
Theory into Practice
"It was ridiculously simplistic, really," he recalls, "to see if we could get people to eat the same plant-based diet as other countries in order to slow, stop or even reverse heart disease; to change patients' metabolism/bio-chemistry."  So Dr. Esselstyn and his wife Ann determinedly started it themselves in April 1984. Within the first several months Dr. Esselstyn's cholesterol dropped to 119, from 190.
 
He then went to cardiology at Cleveland Clinic to seek patients who would agree to the diet. The patients in Dr. Esselstyn's initial study came to him with advanced coronary artery disease. Despite the aggressive treatment they received, among them bypasses and angioplasties, many were told by their cardiologists that they had less than a year to live. Within months on Dr. Esselstyn's program, their cholesterol levels, angina symptoms, and blood flow improved dramatically. Twenty years later, compliant patients remain free of symptoms. Here are the documented results:
 
Drop in cholesterol levels: After 5 years on Dr. Esselstyn's plant-based diet, the average total cholesterol levels of his research group dropped from 246 milligrams per deciliter to 137 mg/dL (Above 240 mg/dL is considered "high risk," below 150 mg/dL is the total cholesterol level seen in cultures where heart disease is essentially nonexistent.) This is the most profound drop in cholesterol ever documented in the medical literature in a study of this type.
 
Cardiac events: The 17 patients in the study had 49 cardiac events in the years leading up to the study, and had undergone aggressive treatment procedures. Several had multiple bypass operations. After beginning the eating plan, there were no more cardiac events in the group within a 12-year period.
 
Angiogram evidence: Angiograms taken of the participants in the study show a widening of the coronary arteries, and thus a reversal of the disease.
 
Within 3-4 weeks of starting this nutrition plan, the cap over the plaque is strengthened so it cannot rupture. High fat foods such as oils, avocados, dairy, meat, fish...all destroy the endothelial cells. Endothelial cells produce nitric oxide which insures smooth blood flow and strengthens the cap over the plaque.  As Dr. Essestyn so creatively put it: "Anything with a face, that flaps its wings, wiggles a fin, is not allowed because it injures the endothelial cells." 
 
In 1991, Dr. Esselstyn served as President of the American Association of Endocrine Surgeons, That same year he organized the first National Conference on the Elimination of Coronary Artery Disease, which was held in Tucson, Arizona. In 1997, he chaired a follow-up conference, the Summit on Cholesterol and Coronary Disease, which brought together more than 500 physicians and health-care workers in Lake Buena Vista, Florida.

His scientific publications number over 150. In 1995 he published his bench mark long-term nutritional research arresting and reversing coronary artery disease in severely ill patients.  That same study was updated at 12 years making it one of the longest longitudinal studies of its type.  It is most compelling, as no compliant patients have sustained disease progression.  Today, 20 years later compliant patients continue to thrive.

Proundly Simple:
The following is an exerpt from Dr. Esselstyn's article:Resolving the Coronary Artery Disease Epidemic through Plant-Based Nutrition, published in Preventive Cardiology, 2001; 4: 171-177:
 
Replace the "Food Pyramid"
"An integral part of this offensive must be to eliminate the toxic food environment. Look at the so-called Food Guide Pyramid, the familiar geometric symbol used to promote the recommendations by the U.S. Department of Agriculture and the Department of Health and Human Services. It is laden with dairy products, animal products, and oils, which are the essential building blocks for coronary artery disease. In addition, from a design standpoint, the choice of a pyramid is potentially confusing and misleading. Some viewers may be led to believe that the foods at the top (meats, sweets, and fatty foods) are the most helpful, when in fact they are the most harmful. To avoid such sources of confusion, we should eliminate geometric figures and promote 3 simple food categories: safe, condiments, and unsafe.

Safe: whole grains, legumes, lentils, vegetables, and fruits
Unsafe: oils, dairy foods, meat, poultry, and fish (not regulated by inspection, and frequently contain unacceptable levels of PCB's, dioxin, and mercury.)

In addition, we should recommend dietary supplementation with a daily multivitamin, and, for those over 50 years old, an additional 1,000-1,200 mg calcium and 600 to 800 IU of Vitamin D. These recommendations are in concert with those of the expert faculty from the First National Conference on the Elimination of Coronary Artery Disease."
 
Dr. Esselstyn's enthusiasm for educating and inspiring his patients is evident. "It is so powerful when patients recognize that they are the locus of control to protect themselves from having another heart attack. When properly counseled, patients comply not only one year, but for the rest of their lives." Dr. Esselstyn and his wife have now been following a plant-based diet for 25 years. They work together to counsel patients both in Cleveland, where they live, and in summer at the farm in upstate New York where Dr. Esselstyn grew up. Dr. Esselstyn concentrates on the medical details, and Ann focuses on healthy foods and how to prepare them.

His book, Prevent and Reverse Heart Disease offers readers the same simple, nutrition-based plan that dramatically changed the lives of his patients forever. With this eating plan, sufferers of heart disease will maintain cholesterol levels low enough to ensure that they will never have a heart attack. Best of all, the book offers more than 150 delicious recipes that Dr. Esselstyn and his wife have developed over the years-showing readers how easy it is to enjoy their new way of eating.

For more information, articles and studies, please see Dr. Esselstyn's website: